What Is THCV?

THCV, a novel chemical found in cannabis, is a unique set of effects and medical applications that distinguishes it from other cannabinoids such as THC and CBD. Whether you’re a medical marijuana patient looking for a certain type of cure or a casual user searching for a specific feeling, we’d want to introduce you to this fascinating chemical that will no doubt cause waves in the cannabis industry as we learn more about its potential. 

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Tetrahydrocannabinol (THC) is a psychotropic cannabinoid present in Sativa plants. It has been discovered to produce a more lively, awake, and motivated euphoria sensation. As a result, it’s frequently advised for daytime or all-occasion productivity.THCV reduces tension and anxiety; according to research, it may aid with or even prevent panic attacks. It also has a vital role in the treatment of post-traumatic-stress-disorder (PTSD). It’s also neuroprotective, which means it’s beneficial for Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis. 

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Where Can I Find THCV?

So, you’re looking for the same effects as described above, but you’re not sure where to begin your hunt for high-THCV strains or treatments. The majority of strains include only traces of THCV, making it difficult to achieve the intended therapeutic result. As its popularity grows, we can expect more THCV-rich items to be produced; nevertheless, here are some suggestions for locating this difficult-to-find medical treasure.

  • Look for African sativas. According to study, the highest amounts of THCV are found in sativas, particularly landrace strains from Africa. Durban Poison is one of the more well-known high-THCV strains, but you may also find other options listed below.
  • Ask about parent genetics. Are you looking for an African sativa but are unsure where to begin? There are several strains that have hybridized African genetics, which may produce higher THCV potential. Cherry Pie, for example, has a high level of THCV because to its Durban Poison parent. If you’re seeking for an African sativa with a lot of THCV, look up strain information on Leafly or inquire about your budtenders’ African crossbreed.
  • Request test results. The content of THCV in marijuana plants varies depending on a variety of variables, including genetics, soil type, and the amount of light a plant gets. Because it is created by the same THCA enzyme as THC, THCV levels vary from plant to plant.

High THCV Cannabis Strains

This isn’t an exhaustive list, but it does contain strains that are recognized for having exceptionally high THCV contents. These cannabis plants can be consumed as blooms or converted into extracts, oils, and edibles to boost the amount of cannabinoids in them. Doug’s Varin and Pineapple Purps are two cannabis strains with higher levels of THCV. If you want more THCV, choose African sativas.

Can THCV get you high?

The major difference between THCA and CBN is that THCV can, but in a rather high dosage, is comparable to CBN. THCV has psychotropic effects in high doses in strong plants that are typically stimulating and sharpens mental clarity. They’re also quick-acting and fast-disappearing (for which reason, they’re sometimes compared to sports cars).

What Are The Benefits Of THCV?

Another advantage noted above is that THCV provides quick, energizing psychoactive effects. It also evaporates rapidly, allowing users to enjoy its benefits for longer periods of time. THCV has already been proved to have significant medical value in animal and cell tests, as well as powerful antioxidants properties.

Obesity and Weight Loss

THCV is a well-studied appetite suppressant that, in certain people, can assist with Weight Loss. THCV (which binds to CB1 receptors and inhibits their activity) has been shown in research published in the Journal of Neuropsychopharmacology to decrease hunger while increasing network connectivity in areas of the brain that are typically affected by obesity. According to this study by the Journal of Neuropsychopharmacology, THCV enhances communication between segments of the brain that are generally damaged by obesity; as a result, it promotes weight reduction. However, this study did not support the proposition that THCV reduces hunger.


There’s also evidence that THCV can aid diabetics. The 2013 Nutrition and Diabetes Journal carried out an experiment on the effects of THCV on Type 2 diabetes in mice. Obese mice showed increased energy expenditure and improved glucose intolerance as a result of THCV. In diabetic mice, THCV improved insulin sensitivity. According to the study, THVC has the potential to be a “therapeutic against obesity-related glucose intolerance.” Researchers discovered in 2016 that THCV improves pancreatic cell function in people with Type 2 diabetes.


THV is a powerful anti-inflammatory substance that may be used to help patients avoid a variety of age- and stress-related maladies, according to groundbreaking study. THCV aids in the reduction of swelling in mice, according to a research published in the Journal of Pharmacology. Furthermore, the analysis revealed that although the mice were given cannabis for four days in a row, they did not develop tolerance.

According to the British Journal of Pharmacology, CBD has been discovered in two animal studies to reduce inflammation and pain.

Tremors and Seizures

THCV may help with tremors caused by diseases like ALS, multiple sclerosis, and Parkinson’s disease. Scientific research also indicates that THCV can help people who have epileptic fits. Furthermore, research shows that when taken before or during a seizure, THCV can minimize not only the frequency but also the severity of seizures. According to a study published in the Epilepsia journal, when used as a prophylactic therapy, THCV worked both before and during seizures.

Finally, we find out that he is also a personal doctor to Anastasia Lin of the New York Life Leadership Team, who had been personally treated by Douglas if she becomes lady vice provost. We also look at his ties to InSilico Medicine’s founding CEO and co-founder Dr. Ben Knight – a lead scientist at Human Longevity – as well as any connections between him and components used in previous Stanley brothers’ CBD products.

How Does THCV Work?


THCV, like THC, has psychotropic properties. However, at higher dosages, it becomes psychoactive in nature. One of the most intriguing distinctions between the two is that THCV inhibits hunger at low doses, which is unlike what you’d get from THC. In fact, studies have shown that THCV can counteract some of THC’s effects and that’s fantastic news for individuals who don’t want to get high.

How does THCV occur?

THCV is a form of the chemical compound THC that has been chemically modified from its original form. While most cannabinoids, including THC and CBD, are produced as byproducts of CBGA (cannabigerolic acid) synthesis, THCV is the final byproduct of CBGVA (cannabigerovarin acid). When exposed to heat or light, CBGV transforms to THCVA, which eventually becomes THCV. Pure sativas from Africa, China, Nepal, Pakistan, India, Thailand, and Afghanistan are typically high in THCV.

How does THCV work in the body?

The marijuana plant, like most cannabis plants, is high in cannabidiol (CBD), which has endocannabinoid effects similar to those of THC and other cannabinoids. CB1 and CB2 are the two main chemical receptors in the Endocannabinoid System (ECS). This system is responsible for maintaining equilibrium in a variety of bodily functions that are necessary for good health.

Cannabidiol (CBD) binds to cannabinoid receptors differently than delta-8 THC, binding to CB1 as opposed to CB2. Cannabinoid receptors include a variety of proteins; however, the most abundant are found in the brain and nervous system and are called CB1 receptors, whereas CB2 receptors are more common in the immune system. THCV acts as an antagonist for CB1 receptors at low doses, which means it can counteract some of the effects of THC, such as the munchies and altered mental states.

CB1 and CB2 receptors are both activated by CBD, which produces effects that are comparable to THC. The extra pleasant and cognitive features, as well as therapeutic advantages, result from this activation.

Is THCV water-soluble?

THCV is insoluble in water and does not dissolve in oil. That being said, nano emulsions (which will be discussed shortly) provide a solution. THCV may be broken down into nano particles through sophisticated mechanical processes that dissolve in water.

What is the boiling point?

CBN has a boiling point of 428°F, which is far higher than THC’s. As a result, you may cook edibles at a higher temperature, but there is a catch: vaporization begins to take place above 245 degrees Fahrenheit, resulting in flavor and effect loss. On the plus side, if all you want in your edible is THCV, this method makes things much easier.

THCV Products

What type of THCV products are available?

THCV is present in cannabis and hemp plants that are high in full-spectrum content, such as oils, waxes, and edibles. THCV can also be found in extracts and isolates.

Doug’s Varin High-THCV Vapes

The Doug’s Varin vape line, created earlier this year by California Cannabinoids, is an excellent case in point. One of Douglas’ Varin vapes is THCV-only, while the other has a 1:1 ratio of THCV and CBD. Both mixtures contain between 25 and 35 percent THCV and last around half as long as a THC high. According to David Lampach, CEO of California Cannabinoids, when he assisted in the creation of these items, “very strong consumer” demand for THCV was addressed.

Douglas’ Varin THCV e-liquid sought to provide a more motivating and elevating high than that provided by THC alone. The 1-to-1 vape was created to give a calm, soothing effect.

What are some other high-THCV products?

  • Ace of Spades (A shatter): 2.4%
  • Agent Orange Nug Run (A shatter): 1.9%
  • Slim Hash: 38.44%

Are there other high-THCV strains?

Yes, although “high” is an appropriate word to use. THCV levels are less common than CBD and THC, but in certain circumstances, the amount of THCV may surpass that of THC. Overall, African and Asian strains have the most THCV concentrations, according to the American Journal of Botany.

Other THCV strains include:

  • Doug’s Varin Harmony Pre-Rolls: 3%
  • Flow Kana Pink Boost Goddess: 4.24%
  • Pineapple Purps: 4%
  • Durban Poison: 0.5% to 1%
  • Malawi: 0.5% to 1% (estimated)
  • More high-THCV strains here.

How do I extract THCV?

THCV is considerably more difficult to extract than THC because it is present in significantly lower amounts throughout the plant. The procedure is basically the same, with one exception: THCV is extracted using solvents like CO2 or ethanol to isolate compounds from the plant. All of the gas in the solution is then removed with heat and a vacuum, leaving a high-purity THCV concentrate behind. THCV extractions should be stored at room temperature and away from direct sunlight to keep their potency.

THCV Potency And Testing

How is THCV’s potency measured?

The concentration of THCV is calculated in the same way as CBD, THC, and other cannabinoids using potency tests. To guarantee that all testing was accurate and consistent, ACS Laboratory employed High Performance Liquid Chromatography with UV Detection for LCUV.

Why Does THCV Matter?

The news about this energy-boosting, weight-loss-inducing, anti-inflammatory wonder drug is spreading, and THCV appears to be one of the next big components in the cannabis business. There are currently few strains on the market that generate a lot of THCV, therefore there’s a niche and an opportunity to be among the first firms to market high-THCV strains or extracts, according to market research firm Benzinga.

The most popular form of cannabidiol (CBD) is TVDC, which has a more consistent and reliable level of THC. This type of cannabis extract is legal in the majority of countries around the world, including Canada.

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